2 Mature Follicles And Trigger Shot

I had my trigger shot on cd13 with follicles at 22 and 15mm. We use cookies to give you the best possible experience on our website. 6mm the day before Ovidrel shot (surged on my own). I have never had any blood work. I still have to hear it from the nursing team. – 6/9 7:00am ovulation kit negative; 9:30pm Pregnyl (HCG) trigger; see this post. When the follicles are mature and ready the hCG trigger (human chorionic gonadotropin) to help the eggs mature and release from the follicles. Follicles in the ovary begin developing under the influence of a complex interplay of hormones, and after several days one or occasionally two become dominant (non-dominant follicles atrophy and die). I started to ovulate on my own once my biggest ones hit 17 and I still didn't get pregnant for a host of reasons that I won't bombard you with lol. I found this very intriguing but wondered the validity of it. Also, if you're using an OPK and you get a +, you do not need the trigger. 3 before age 28 to 3. When you take the shot, it will help complete the eggs' maturation process and. On 50mg clomid days 3-7, I made 3 mature follicles and a bunch of small ones that won't mature. 7 urinary lining. Hi Mrs Bubble My day 7 scan wasnt very positive on my first round of treatment (IVF/ICSI) follicles they said they couldnt measure and even asked if i was injecting the drugs, i went back on day 11 and i was ready to take the trigger shot and had 7 follicles, 4 were eggs and 1 fertilised normally one delayed fertilisation my little boy is now 4 from that cycle. I had an ultrasound today and I have 19. January 2010 - Cd 3 baseline ultrasound (cyst is GONE!), cd 3-7 5mg Femara, Cd 7-12 75units Follistim injections, cd11 follicle tracking ultrasound 2-3 good follicles (45 total), Cd13 ultrasound 1-20mm on right, 1-17mm on left, HCG trigger shot, Cd 15 IUI, 1 dpo start Prometrium 100mg 2x/day, BFN. 25);median (in-. The doctor didnot suggest a trigger shot. Last edited by Seelie on Sat Oct 29, 2011 2:39 pm, edited 1 time in total. Follicles are initially a single layer of epithelial like cells around each from BIOL 204 at Vanguard University. Adam mixing the HCG "trigger shot" to be administered at 11:15 PM PST. Find more Best Price and More Promotion for 2 Mature Follicles And Trigger Shot Reviews 2 Mature. Brief Answer: You have good chances of pregnancy Detailed Answer: Hi, I understand your concerns about IUI. Recombinant Chorionic Gonadotropin (r-HCG): 250 mcg subcutaneously once 1 day following last dose of follicle-stimulating agent. Chances are that you will only release 2 mature eggs, the trigger shot gives them a little extra boost too so by the time they release they should be between 20mm and 24mm and those are good sizes. There are different medications that can act as a trigger shot. Have the IUI from hell - nurse has to use a tenaculum to hold my cervix in place. The shot mimics your natural LH surge, and it allows the follicle(s) to rupture and release the egg(s). She had two mature follicles at 19 and 22 mm and was given a. I am currently at the tail end of stims for my third IVF cycle and today's u/s measurements were 1. cd9 – 125; cd 10 – Ultrasound and bloodwork: One follicle – 14mm, a bunch of smaller ones. On day 12 my largest follicle would usually be around 20-22 mm. Re: IVF/ICSI ladies - how many follicles and how many eggs? Thanks so much, everyone. I am very worried that I might end up with twins or more. For the last three months I have had an ultrasound to confirm a mature follicle and then a trigger shot to induce ovulation. 5 and another at 12. This isn't my ovary, but an example. Posted in miscarriage, Pregnancy, RPL, The Waiting Season, TTC, Two week wait Tagged 3 mature follicles, 5 DPO, asprin, cycle 10, dexamethasone, follistim and clomid cycle, great insemination timing, lesbian ttc, pomagranate juice tww, repeat chemical pregnancies, RPL, the waiting season, trigger shot, ttc, two moms, two week wait, TWW, ulcer. The hCG trigger shot is a dose of the hormone human chorionic gonadotropin, which normally is produced by the body after implantation of a fertilized egg into the uterine lining. This time well wait till they are between 2. I usually have pretty bad pain when I ovulate (doesn't matter if it's. We were in same position a few months ago on our 2nd cycle, we decided to go ahead, 2 follicles we got two good eggs and 1 lasted till day 5 but negative result. Timing of IUI after hcg trigger shot. This month, I have two mature follicles, one on each side. I want to know exactly what is going on. When several mature follicles develop the couple and the fertility specialist can discuss multiple pregnancy. When the cohort of follicles is thought to likely include mostly ‘mature oocytes’, a final trigger shot is used to allow the final maturation of the oocytes. The second ultrasound will show (hopefully) how big the follicles are (if there are any) and if they are the right size then we will get the go-ahead to trigger (with Ovidrel "trigger shot") and then Dr. Good luck and baby dust ****. Level of estrogen (estradiol) The estrogen level directly correlates with the number of follicles in the ovaries and is used to help your physician determine the appropriate medication to use for the trigger shot. This injection does help initiate the egg release from the follicle. But that one stuck and is due in Feb. With my one little ovary, I have about 5 follicles as well, most of them are pretty good size, on their way to being pretty mature, 5 follicles for one ovary is pretty decent. Each month at the onset of the menstrual period, between 10 and 20 follicles will normally reach the antral stage, at which they are ready to grow into mature follicles under the influence of those hormones. My RE would like to see a greater disparity in size between the two largest ones and the rest, but we're still a go to trigger at the end of the week. The Clomid for me has been doing its job, which is good to hear!! According to my RE the “goal” is to get as many follicles between a 16 & 20 without them getting too big before the trigger shot. Follicle and iui is over i'm currently on clomid 50mg but i was taking clomid, can amoxicillin expire on 6/1. I want to know exactly what is going on. 5mm, 14mm and 13. The trigger shot. Timed intercourse (with Pre-Seed) day of trigger and next day: BFN. Usually the higher the success rate for the IUI procedure is related to how many mature follicles release during that month. Objective: To evaluate the percentage (%) of mature oocytes retrieved in patients with a previous history of >25% immature oocytes retrieved who were triggered with gonadotropin-releasing hormone agonist (GnRH-a) and human chorionic gonadotropin (hCG) to induce oocyte maturation. Hi, the gonadotropin injection and the trigger shot are two different things. Clomid/timed intercourse (disastrous) round 2: started 50mg of Clomid on CD2 for 5 days. 4 ± 1 follicles, while the mean diameter of the lead follicle was 21. I ended up developing a 22mm follicle and a 14mm follicle. If you are taking the hCG trigger shot, you will be monitored closely by your doctor. [This is when you will usually begin to feel wet {sorry TMI} - the cervical mucus ] maybe like CD10-12 on a typical 28 day cycle. I received my shot today. If you are going to be getting the HCG trigger shot, chances are your doctor will prescribe a medication like Clomid in order to help prepare your follicles for ovulation and make sure that you ovulate properly. During each reproductive cycle, several follicles begin to develop. I would still only produce 1-2 MATURE Follicles that were ready for the ovulation trigger shot. advice: when to trigger - follicle size and estrogen level - posted in Assisted Conception - General: Hi Girls, I am after opinions please! I am doing IUI, with injectables, and yesterday had a. Commonly, this is known as the "trigger shot. As far as I know, the trigger shot has no bearing on multiple pregnancies (but I'm not a medical expert). Follicles grow approximately two millimeters a day and size is an average. :))) I am curious if both of my mature follicles will release an egg or will only the most mature egg release. Some clinics aim a little lower though, and follicles do continue to grow and mature after the trigger. I agree with Paula, 14-15+mm could produce a mature egg, but the general rule is 18. For me, the goal was to develop and subsequently harvest 12 to 15 of them, but for some women, that number is lower or higher. When there are follicles around 15mm, they usually don't go, but they can. I've never had the trigger shot, but as someone who normally would have 2 months + long cycles, my follicles were mature(and I ovulated on my own) around day 16 on Femara. 16 mm follicle today 21 mm follicle on cd 16! - FertilityCommunity. While every clinic is different, the trigger shot of HCG (given right before egg retrieval) is administered around the eighteen to twenty millimeter mark. 1 dominant follicle, 2 immature follicles at trigger on 5/9, IUI on 5/11. *APRIL 2011 Fifth Medicated Cycle- Gonal F 37. However, in patients with diminished ovarian reserve (DOR), there is a. I’m a little concerned that the eggs could be post-mature… I found a study showing the highest level of mature eggs from follicles 12-19mm on the day of trigger. The egg retrieval occurs approximately 34-36 hours after the trigger shot. The hCG trigger injection is a medication known as a human chorionic gonadotropin and is used after other fertility hormones, such as clomiphene citrate or menotropins, to induce ovulation (release of the egg from the ovary) or in women undergoing an assisted reproductive technology (ART), to induce final maturation of the eggs. http://www. In clomiphene + HMG cycles, the number of follicles decreased from 5. I had four mature follicles and lots of smaller ones. When I saw my RE yesterday for my ultrasound he told me I had three follicles over 20mm on one side. The shot then tells your body to mature the eggs within the follicles and prepare to ovulate. There's a decent chance the 16 mm one will mature to a potential egg during that time and a very small chance one of the smaller ones will as well, although I'm not holding out much hope. ) alone, or co-triggered by HCG plus 0. And a trigger shot’s timing requires clinic expertise and patient vigilance. Your provider is timing when the eggs will be mature and almost ready for ovulation but not quite ovulation because we want to get those eggs first!. Hi cocoloco, I had two 50mg cycles. I went in on CD11 for my first follicle-check ultrasound on Sunday, but there were not any that were big enough. Design: Retrospective cohort study. I had an ultrasound today and I have 19. Ovaries produce and release two groups of sex hormones—progesterone and estrogen. My E2 was 1193, so my RE told me to trigger 3 hours after this ultrasound. He was so confident that it would be mature enough, he went ahead and wrote out a RX for my HCG injection and told me he would advise me to pick it up today!! So as of now, the plan for tomorrow is to go to the ultrasound and get my trigger shot, we will then have timed intercourse on Wednesday night. Has anyone had success with trigger shot?. The follicular phase occurs on (Days 1-13) and lots of FSH (Follicle Stimulating Hormone) released by brain-affects ovaries where "selected" primary follicles begin to mature - Menstruation occurs (~ days 1-5). Table one compares the mean values of different aspects studied between the two study groups, and the difference in age, FSH, and LH between the two groups was statistically. DesignRetrospective analysis to determine the size of follicles on day of trigger contributing most to the number of mature oocytes retrieved using generalized linear regression and random forest models applied to data from IVF. My dr would not even do IUI if you had more than 2 or 3 follicles, and he thought it was wreckless of drs who did. 2 Estrogen: 222 Follicles: 10 follicles Increased to 300 Gonal F & 150 Menopur. 4 mature follicles after clomid Order Now! Very cheap pills online, Secure and Anonymous. The RE made the decision to stim me for one more day, and. HCG trigger shot, follicle at 24mm after 100 100 Mg Clomid And Hcg Shot mg of clomid: Hello ladies, Today got the shot. The trigger shot can affect your readings. Hitkari - Please write to let us all know your feelings on the ideal follicle measurement on the day of the HCG trigger. When the largest gets in about the 18-24 range, you will trigger and do IUI. I have been told they like to see them at least 16 but I know someone who concieved her son when her largest folly was only 14 so that is still possible. No mature follicles at CD9 scan, so 100mg for 3 days; still nothing ready, so 150mg for 3 days. They gave me a trigger shot and told me to bd for the next 3 days and come back next Friday for labs. I took an HPT this morning at 6 DPO just to be sure that the Ovidrel HcG shot was out of my system, because that is the one medication I took that could show a false positive when it comes time to actually test for pregnancy. Good Luck!! 1 Celsius (96. At first I was disappointed with the news two days ago that we most likely only had 6 mature eggs, but after today’s ultrasound, the nurse said we should get at least 1 or 2 more than that in the smaller follicles. Recombinant Chorionic Gonadotropin (r-HCG): 250 mcg subcutaneously once 1 day following last dose of follicle-stimulating agent. I was told the trigger shot works more quickly than that. It is important to time the shot within the indicated window, as egg retrieval will be scheduled for the peak fertile time after ovulation: generally 35 to 36 hours after the trigger shot. SO my planned IUI is both Sunday, & Monday. b) the trigger is still in my system. Would you go ahead with ivf? - posted in IVF/FET/IUI Cycle Buddies: Thats true. Most look for the 18mm follicles and go for it. By days 10-13 estrogen levels in blood are very high. Just went on Femara for the first time this month and on CD13 only had one follicle measuring at 16. According to Medline Plus, hair grows 1 inch every few months. advice: when to trigger - follicle size and estrogen level - posted in Assisted Conception - General: Hi Girls, I am after opinions please! I am doing IUI, with injectables, and yesterday had a. When you take the shot, it will help complete the eggs' maturation process and. ) My left ovary had 4-5 follicles but they weren’t as large. 5mm, 16mm, 13mm, 12. I went for a ultrasound today 1/19 and had 1 follicle at 18. There are so many factors and this is why getting pregnant, whether by IVF (in vitro fertilization) or not is such a lottery and such a miracle. [This is when you will usually begin to feel wet {sorry TMI} - the cervical mucus ] maybe like CD10-12 on a typical 28 day cycle. I got the HCG trigger shot with all of the cycles. How does this trigger shot work? Ovidrel is a gonadotropin, a hormone normally found in the body which helps with ovulation. about trying a trigger shot and while they've said they're open to me trying it if I really want, they seem to think continuing to use the OPK strips would be best. 3 mature follicles. I am doing the Ovidrel ovulation trigger shot tonight and have an IUI scheduled for Sunday morning with the spermcicles! 🙂 The trigger shot will increase their size as well as it being another 36 hours for them to grow and get. Two 24mm and one 22mm, I believe, and I was given the go ahead to give myself the ovidrel shot. I recently started going to a new doctor who is now doing follicle tracking by ultrasound. Good luck! Stay positive. I am just curious what your follicle sizes were at the time of trigger? Mine were: 18. You are absolutely right, this is hard to predict. Maele-I also use to Ovidril pre-filled syringe for timed intercourse after by follicles have reached a mature size with the assistance of Gonal F and Menopur. Ovidrel is a type of injectable medication that's also known as a "trigger shot. Estradiol levels help us to determine when the follicles are mature, so we can time the hCG trigger properly, and maximize the number of mature eggs we retrieve. a) its too early. The trigger I heard can further mature eggs as well, so it's possible my e2 was even higher by the time I actually ovulated and I couldn've had. where I want to test, but I can’t test. Our issues were male factor and we were using donor sperm. Oocyte retrieval was performed after 35-36 h of ovulation trigger. If you ovulate regularly then you may not want/need to do a trigger shot. The HCG trigger shot is to help with the timing of the IUI. 15DPIUI MMC 8w4d 2nd IUI Same protocol as above 1 mature follicle on the right. On 50mg clomid days 3-7, I made 3 mature follicles and a bunch of small ones that won't mature. My oestradial (spelling?) level was 4000 two days before which suggested there were at least 4 eggs, so where did they go?. We've got married Dec 24, 2006. Ovulation will happen 38 to 40 hours after an injection of hCG when there are one or more mature ovarian follicles. Yes, the fact that you have 5 mature follicles ready to go is wonderful and increases your chances significantly. First cycle went well detected surge and had timed intercourse. However, ovulation induction can increase the risk of multiples. HCG Trigger? Follicle sizes?: Hi everyone, I feel like I have become a frequent poster haha, so I'm sorry about that. com or call us at 949-726-0600 if you have questions or are ready to schedule a consultation. However, advanced maternal age or history of failed IUI may warrant triggering with 4 follicles. You can often get clues about this if you had plenty of follicles but not many eggs recovered as the synthetic HCG sometimes leaves the eggs still ‘sticky’ and difficult to flush out of. I had a scan on CD11 and I had three follicles measuring 14. My lining is 9. I only have one tube and I had 2 mature follicles with the trigger shot and IUI, my chances to get pregnant were 25% My change of having twins was less than 10%. 2 mature follicles definitely means you have a chance of having twins, no doubt. If no cysts are present, which is almost 100% of the time, than Clomid or HMG is started on the appropriate day of the cycle and ultrasounds are done every 2-3 days to. They gave me a trigger shot and told me to bd for the next 3 days and come back next Friday for labs. I usually Ov 24-36 hours after the trigger shot, so we feel comfortable with that too. Is chances multiple pregnancy?. Just a thought. OHSS usually happens within a week after you receive an HCG injection. Said not quite ready yet and to come back in 2 days later. Thinking of. Sometimes the eggs retrieved during a save were immature and needed time growing in the lab before introducing the syoungihmm. As follicles spontaneously reach maturity in the natural cycle their inner dimensions range from 17 to 25 mm (9). What is Estradiol? Estradiol (E2) is the primary estrogen, the major female reproductive hormone, and is produced in your ovaries. I've never had the trigger shot, but as someone who normally would have 2 months + long cycles, my follicles were mature(and I ovulated on my own) around day 16 on Femara. Went for ultrasound on 15. We had to run to the Walmart across the street and pick up the shot (not covered my insurance which is crazy since we're supposed to have a $22,000. Ovidrel (choriogonadotropin alfa injection) is a fertility drug used to enhance and trigger ovulation. Just had my 10 day scan after first cycle of clomid and I have 3 mature follicles. Do a refill of miracle drugs commonly used to give myself the 10 dpo i am on dlife. If the issue is there are too many follicles but just not maturing quite to the right size, again, the question you need to ask is whether you do the trigger shot to complete the cycle or let the body do it own work. Follow up ultra sound on October 17th show 2 mature follicles in my left ovary! One at 18mm, the other at 28mm. The use of hCG induces ovulation in about 95 percent of women, and will get. Bump up to 125 IU follistim tonight. So, our 2nd try at insemination will be tomorrow morning, and it is going to be an EXHAUSTING day!. I got the HCG trigger shot with all of the cycles. Ovaries produce and release two groups of sex hormones—progesterone and estrogen. I had a mature follicle each cycle and didn't ovulate even with Ovidrel trigger shot. I am on my third cycle of clomid 50mg and also on my second hcg trigger shot. The doctor didnot suggest a trigger shot. Free shipping and returns on "2 Mature Follicles And Trigger Shot Online Wholesale" for you buy it today !. Mature follicles Srfoshee. Had stretchy cervical mucus minutes before the shot. Follicles more than 21 mm size are not good for the good quality of egg. If you ovulate regularly then you may not want/need to do a trigger shot. Thanks to the Clomid, I have produced 9 mature follicles (3 reaching 18mm). He wants to trigger today to prevent the smaller ones from catching up, since the risk of multiple pregnancy would be too high. My insurance covers drugs, 100%, so after getting over my fear of needles I consulted with my FS and she said to do perhaps 3 more IUI's with gonal f, and a trigger shot. Or maybe it was my body? It’s hard to know since we’ve never monitored my ovulation off drugs. I usually Ov 24-36 hours after the trigger shot, so we feel comfortable with that too. 5 mg of Femara cd 3-7. Thinking really positive thoughts. Lupron is a synthetic form of GnRH,( gonadotropin releasing hormone), which is produced in the hypothalamus to stimulate anterior pituitary gland to release. As they grow and develop, your egg follicles secrete estradiol, helping to trigger the rest of the reproductive cycle. Month 2: 50mg clomid, 4 follicles, timed intercourse. I had my trigger shot on cd13 with follicles at 22 and 15mm. My E2 was 1193, so my RE told me to trigger 3 hours after this ultrasound. How much do follicles grow a day? 2. I have a 4 part question: 1. Good luck! Stay positive. I was told to do the trigger shot tonight from 6-8pm and a IUI for sunday 1/21 so 36hours later. And he estimates that by tomorrow (when I trigger) I’ll have 3 mature follicles and 1 almost mature (15, 16, 17, and 20). Normally, the others recede (stop developing) and just the dominant one releases an egg when you ovulate. Have the IUI from hell - nurse has to use a tenaculum to hold my cervix in place. I've read that the trigger shot will force all mature eggs to. Visit us at https://www. Now im on CD13 and i got an positive opk. Compared with monofollicular growth, success rates increased by 5, 8 and 8% when stimulating two, three and four follicles. There are possible 5 mature follicles. Has anyone had success with trigger shot?. When your LH surges it will attempt to ovulate follicles with mature eggs but there is really to way to know which follicles have mature eggs and how many of those will release. As far as I know, the trigger shot has no bearing on multiple pregnancies (but I'm not a medical expert). I take Clomid 50mg on CD 3-7. That pregnancy though, only showed one fetus. The same trend was observed when the rate of MII oocytes was calculated per retrieved COC (MII/COC rate, 59. Please read more about the hormones used below: Lupron (Leuprolide Acetate). Not many people would know about the Hcg trigger shot but if you have been long enough on the journey and thought about assisted reproductive technique, then you would surely have come across the injection. The woman has an ultrasound which measures the size of the follicles in the ovaries and determines if they are large enough to induce ovulation. So, I'm really nervous that my RE had me take the trigger shot before my follicles were mature and as a result, I don't think I ovulated. What is Estradiol? Estradiol (E2) is the primary estrogen, the major female reproductive hormone, and is produced in your ovaries. Free shipping and returns on "2 Mature Follicles And Trigger Shot Online Wholesale" for you buy it today !. leading follicle that maximizes the probability of pregnancy, with lower rates for both smaller and larger sized leading follicles. It's known to be the pregnancy hormone. The eggs in these follicles do not mature and. Commonly, this is known as the "trigger shot. My lining is 9. When several mature follicles develop the couple and the fertility specialist can discuss multiple pregnancy. Mild reactions may occur in the sensitive individual when the blood alcohol concentration is increased to as little as 5 to 10 mg per 100 Clomid and HCG trigger shot? Fertility Treatments. Also, he said the lining of my uterus looks good, it’s a good thickness to be able to get pregnant. Had 2 very large mature follicles. We tried to look at it from a practical view as its a hard decision to make, consider you fiances and whether you'll try again. I don't think the 2 small ones will ovulate on Monday. I had a laparoscopic surgery last year to remove masses and check my tubes which showed that one is blocked. My doc had me trigger that morning and come back for an IUI the following day and the day after. Brief Answer: You have good chances of pregnancy Detailed Answer: Hi, I understand your concerns about IUI. (I believe mature follicles are around 20-22 mm. This follicle differs from the others by its size and rapid growth. 1cm and the others were 2. 16 mm follicle today 21 mm follicle on cd 16! - FertilityCommunity. *FEBRUARY, MARCH 2011 Natural Cycles = FAIL. This is because timing of the trigger shot it crucial. And he estimates that by tomorrow (when I trigger) I’ll have 3 mature follicles and 1 almost mature (15, 16, 17, and 20). 7 urinary lining. 8 to 3cm) so at 2,4cm its close to maturing. Details about IVF medication stimulation protocols, including monitoring ovarian stimulation with blood and ultrasound and the number of follicles needed. The trigger is a shot in the butt to “ripen” the egg so that the eggs would ovulate 48 hours later. Prompted by the aforementioned observations, we offered the double trigger to two group of patients demonstrating abnormal final follicular maturation despite normal response to COH, those with low (<50 %) number of oocytes retrieved per number of dominant follicles > 14 mm in diameter on day of hCG administration and those with low proportion. I was giving the trigger shot and told to have sex that night. If your IUI is 36 hours after trigger, I would do your at home vials at 12 and 24 hours so the swimmers can be where they need to be, waiting for the egg to drop!. The hcg shot will make you ovulate - release all of your mature follicles - in 24-48 hours. 7 (left ovary). The nurse was very 'it's up to you what you do', but said there's risk of multiple births if we try this month. I also did an unmonitored cycle, 100 mg of Clomid and one IUI timed with OPK. (subcutaneous injection) Menopur – This hormone is responsible for ovarian stimulation for the development of egg-containing follicles. The trigger shot is usually given 7 to 9 days after your last Clomid pill, but it may be given later than this if ultrasound monitoring finds that your follicles need. One of the follies was 21mm. At what follicle size were you triggered? - posted in IVF Ages 35+: Hi all, I was probably triggered too early last time and this second IVF cycle, we are waiting a little longer. Design: Retrospective cohort study. Most of the time your doctor will give you a medication that induces ovulation (such as HMG or Clomid) and then take the trigger shot. so I know femara is an option. Triggering: Will trigger with Ovidrel (HCG) once I have more than 3 good follicles, hoping for more than 5. Gonal-F ® is a sterile, lyophilized powder intended for subcutaneous injection after reconstitution. It just depends on when your follicles are mature. You can wait for another day and take injection hCG and go for IUI as your follicle will reach 18 mm by tomorrow. I had a couple of medium-sized ones on the right side, but the nurse looks for 20mm or bigger in order to give a trigger shot. all of that being said when I took clomid my RE did not give me a trigger shot until it was 18 mm. If you’re like me and have a lot of tiny follicles all over your ovaries, you need to talk to a doctor about fertility medication to help mature the follicles so you can get pregnant. The Gonal F/Follistim tells the follicles to grow more, while the trigger shot releases the mature eggs from the follicles. I am waiting on a call back from my doctor on when to do the trigger shot and whether to reduce the follistim, as they want to prevent high order multiples. I did U/S this morning and found I have two follicles, one is 18mm and another is 16mm. Also, (HCG) trigger does not slow follicle growth, they should continue to grow until ER. Follicle and iui is over i'm currently on clomid 50mg but i was taking clomid, can amoxicillin expire on 6/1. cd9 – 125; cd 10 – Ultrasound and bloodwork: One follicle – 14mm, a bunch of smaller ones. Only made one follicle and my lining was starting to thin out. Are 16mm follicles typically mature enough to produce an egg?. With 6 mature follicles and 2 catching up mine was at 1830, so we had a possibility of at least 6 of them being fully mature. I agree with Paula, 14-15+mm could produce a mature egg, but the general rule is 18. DesignRetrospective analysis to determine the size of follicles on day of trigger contributing most to the number of mature oocytes retrieved using generalized linear regression and random forest models applied to data from IVF. My lining is 9. Compared with monofollicular growth, pregnancy rates increased by 5, 8 and 8% when stimulating two, three and four follicles. Right: 10 follicles 3x14 mm, 1x15 mm, 1x16 mm, 1x17 mm, 2x18 mm, 1x19 mm, 1x24 mm Trigger shot 10,000 IU HCG 9:30 PM Started Dostinex to prevent OHSS February 1, 2012 (CD 14)- Egg retrieval, 28 eggs retrieved Stomach bug : (February 2, 2012 (CD 15)- Fertilization Report Of the 28 eggs retrieved, 21 were mature and they performed ISCI on these. Follicle sizes don't determine whether the egg is mature or not. For my second COS my Doctor wants to make the following modifications: Luteal estrace cycle day 20, add HGH COS day 7, add FSH with trigger, keep the rest the same as the last protocol. All of them were good sized. My trigger shot was the first hormone injection I had ever received. In stimulated IVF cycles, ovulation trigger is usually performed in the presence of 3 or more mature follicles. I’m a little concerned that the eggs could be post-mature… I found a study showing the highest level of mature eggs from follicles 12-19mm on the day of trigger. Recombinant Chorionic Gonadotropin (r-HCG): 250 mcg subcutaneously once 1 day following last dose of follicle-stimulating agent. This is the hormone of pregnancy, but has a lot in common structurally with the hormone LH and, therefore, can induce. Typically, having the majority of the follicles around 16mm to 22mm is considered ideal. Then, about 10 days of Follicle Stimulation Hormone (FSH) injections help mature the group of eggs to be retrieved a few hours before being spontaneously released by the ovary. 5 yrs -- unexplained infertility -. When the follicles are mature and ready the hCG trigger (human chorionic gonadotropin) to help the eggs mature and release from the follicles. On the day of hCG trigger (d-hCG), due to increased number of follicles, high estradiol levels lead to low endometrial receptivity and thus decreased pregnancy rates in IVF cycles [12, 13]. It showed i have 11. Good luck this cycle, hun. So they will keep monitoring and letting them grow. However, advanced maternal age or history of failed IUI may warrant triggering with 4 follicles. BUT THE NERSE GAVE ME HCG TRIGGER SHOOT WITHOUT CONFIRMATION FROM MY DOCTOR !!! Now I am really worried that my follicles are a little bit two small! Could you let me what is your follicle size when you had your trigger shot!. An hCG trigger shot is meant to mimic the natural LH surge and will help the follicle mature and trigger the release of the mature egg. If you become pregnant during a treatment cycle, OHSS may worsen as your body begins producing its own HCG in response to the pregnancy. 5mm follicle) and let me know it was large enough that we should do the trigger shot right away and do the IUI the next morning. As for size I think it varies with the doctor because I've heard of some people have follicles 20mm(+) but my RE considers them mature at 14. I just finished my first round of Clomid. I agree with Paula, 14-15+mm could produce a mature egg, but the general rule is 18. -Patients should be appropriately pretreated with. On average when does ovulation occur after an HCG trigger shot? I took 5mg of letrozole days 3-7, two mature follicles on day 11, had trigger that day; Femara (letrozole) 5mg days 3-7 and was given pregnyl hCG shot 10, 000iu on cd14 with one mature follicle at 11 pm. The egg retrieval occurs approximately 34-36 hours after the trigger shot. By days 10-13 estrogen levels in blood are very high. Timed intercourse (with Pre-Seed) day of trigger and next day: BFN. I also had one at 11mm, which might grow large enough by ovulation to possibly contain a mature egg. The hCG trigger injection is a medication known as a human chorionic gonadotropin and is used after other fertility hormones, such as clomiphene citrate or menotropins, to induce ovulation (release of the egg from the ovary) or in women undergoing an assisted reproductive technology (ART), to induce final maturation of the eggs. We did timed intercourse after a trigger shot, but not sure if it worked yet. The trigger shot can affect your readings. Basically you may have a total estrogen level of 450 pg/ml at trigger, for two mature follicles and have success, and fail with a total estrogen level of 2000 pg/ml for 20 follicles. See also thyroid gland. I was told to do the trigger shot tonight from 6-8pm and a IUI for sunday 1/21 so 36hours later. They may pick up more follicles in your second scan, but they will probably be quite small. Adam mixing the HCG "trigger shot" to be administered at 11:15 PM PST. I was told that I would ovulate between 24-48 hours after but today it's been 72 hours and my temperatures still haven't gone up. Hmmmmmm a bit disenchanted with Check today. We will let you know exactly when to take the trigger shot. I am on clomid. If the timing of the injection is successful, the mature eggs should be available for fertilization through intrauterine insemination (IUI) or timed intercourse, or for harvesting for in vitro fertilization (IVF). Maybe around 11-12 mm in diameter. Blood work again shows LH surge during mid-cycle scan but told to trigger anyway. I tried two rounds of femara, the first time I had two follicles, so she upped my dose to bring up a third to 10mg, and I only had one egg. Triggered a mature 20mm follicle on "day 10" with 6mm lining on trigger day. Follicle and iui is over i'm currently on clomid 50mg but i was taking clomid, can amoxicillin expire on 6/1. If the issue is there are too many follicles but just not maturing quite to the right size, again, the question you need to ask is whether you do the trigger shot to complete the cycle or let the body do it own work. Hi, Clomid does not always work to produce the mature follicles. HCG not only assists the follicles in maturing, but it also triggers mature eggs so they release from the follicles. And at my last ultrasound (which was the on the morning of trigger day), I had 3 mature follicles, measured at 20mm, 19mm, and 18mm. Hence the importance of having the serum estradiol level tested before trigger, and doing the math. Three mature follicles reptured. For starters it came with two detached needles, individually sealed. Follicle Size before trigger shot Rey_S. Which I make on my own every month. 6 (99% CI 1. I was told to do the trigger shot tonight from 6-8pm and a IUI for sunday 1/21 so 36hours later. Day 5 starts Gonal-f till day 10. So they walked me around to make sure I was safe and then released me. Double trigger refers to the use of either two Lupron injections separated by one hour or the combined use of Lupron and HCG injections to trigger the final oocyte maturation process. Also, follicles continue to grow until they release, usually at a rate of about 1-2 mm per day. DH and I went back for a second ultrasound this morning, CD13. I don't think the 2 small ones will ovulate on Monday. I have one follicle on each side that each measure 12mm. Follow up ultra sound on October 17th show 2 mature follicles in my left ovary! One at 18mm, the other at 28mm. Fast Shipping To USA, Canada and Worldwide. HCG, or human chorionic gonadotropin, is a drug given to mature eggs from artificially stimulated ovaries during assisted reproductive technology, or ART procedures. Visit us at https://www. Then, you will need to be closely monitored by your doctor to determine when your follicles are mature. 94 inch and then ruptures, completing ovulation. I also had one at 11mm, which might grow large enough by ovulation to possibly contain a mature egg. A mature follicle is 20-30mm. Unfortunately my follicles weren’t mature enough to start the process so I have to go back to the fertility specialist on Monday. Egg retrieval: The usual. Approximately, the egg retrieval will take place 36 hours after the trigger shot. Day 8, 9 or 10: Endometrial lining and follicle size are assessed through ultrasound to determine the date of the next visit. So they will keep monitoring and letting them grow. Unless the follicles and eggs can develop optimally, no trigger shot might be capable of yielding good quality eggs. I had two mature follicles in each cycle. The as- sumption became that bigger lead follicles yielded better pregnancy rates [18,19,21,22]. The result is the same, immature eggs that fail to fertilize. Good old Clomid. The biggest were 13, 12, 11, 11, 11, 9. Ideally, fertility clinics would like to see 4 mature follicles before the trigger shot. Triggering: Will trigger with Ovidrel (HCG) once I have more than 3 good follicles, hoping for more than 5. Estradiol levels gradually rise as the follicles grow and mature during the IVF the doctor can decide to trigger ovulation with HCG when your estradiol level is. We tried to look at it from a practical view as its a hard decision to make, consider you fiances and whether you'll try again. The egg retrieval occurs approximately 34-36 hours after the trigger shot. After 36 hours, we plan for IUI. Had double IUI 40 million sperm and 50% motality. When I got home I took about a 2 hour nap and was ready to get up. I am not familiar with an increasing follicle size after rupturing the ovum. Oh and usually about half of all mature follicles will contain an egg, although sometimes they'll find more. The ultrasound went well, I have 12 potentially mature follicles, and I’m ready to trigger tonight. My follicles are generally growing at a consistent rate - sometimes a couple overachievers will get plump very quickly, leaving the rest to play catch up trying to grow mature eggs, but mine have mostly grown at around the same pace which is great because it means it's easier to tell when we should trigger to maximize results. Good luck! Stay positive. I usually get a CD 12 scan and maybe a CD 14 scan as well. Just had my 10 day scan after first cycle of clomid and I have 3 mature follicles. So I don’t respond well to femara. The rest were under 16mm and looking at my history, we should expect 4 mature eggs. Doctors administer this hormone to help time insemination—they want sperm to be waiting for the mature egg (an egg survives for only 12 to 24 hours post. ) I had two good follies this cycle at 19 and 22. Clomid , ultrasound , trigger shot and IUI I have done 3 rounds of Clomid , 1 IUI in the past. For the first IUI with the clomid I had two follicles emerge and then they gave me a trigger shot of Ovidrel. What is the likelihood of having twins? - Answered by a verified OB GYN Doctor. As the follicle matures, it increases in size and the number of granulosa cells also increases, as a result of which the estradiol levels rise progressively. first one developed 12 mature follicles so were told to cancel as too much of a risk, second one was slow to start but ended up with 3 large follicles and trigger on cd13. She thinks they didn't get the one they said broke because I ovulated. He kept me updated on what he was looking for, and proudly told me I had 2 mature follicles on my left side, and a third smaller one. I went for a ultrasound today 1/19 and had 1 follicle at 18. My lining is 9. Does anyone know what the chances of twins are with two mature. Multiple chances also go up slightly when you use the trigger shot. Today my doctor mentioned (kind of in passing) that our timing could have been off because that follicle was bigger than normal and I possibly could have. It is the simplest. Once that is the case and once the lining is appropriately thick (>7mm), a patient is instructed to take the "trigger" medication. If you're undergoing IVF, all the follicles (mature and immature) may be removed from your ovaries to reduce the chance of. There are several brand names for the hCG trigger shot including Ovidrel, Profasi, Pregnyl, and Novarel. I've read that the trigger shot will force all mature eggs to. Licensed and Generic products for sale. The man’s sperm is prepared in the laboratory and then placed directly in the woman’s uterus, increasing the chances that the sperm will reach and fertilise the egg. During fertility treatments, HCG may be given as a "trigger" so that a mature follicle will release its egg. There is 1 egg in each follicle. Today’s ultrasound showed 9 mature follicles so I was instructed to trigger with 2 Ovidrel injections at 10PM. My lining is 9. Freezing embryos. The other day while I was researching God knows what, I came across a blog where the writer mentioned how estrogen levels correlate with follicle counts. Optimal follicle size for iui keyword after analyzing the system lists the list of keywords related and the list of websites with related content, in addition you can see which keywords most interested customers on the this website. In the <38 year group, E2 concentrations measured with the ST AIA-PACK iE2 reagent were significantly lower than those measured with the ST AIA-PACK E2 reagent in the largest follicle diameter categories ranging from 11 to 17 mm. I had failed clomid attempts at 50, 100 and 150mg so the put me on femara, 5 mg and then she did a step up when I didn't quite respond(but still bigger follicles than I had with clomid)7. You will not ovulate. Day 11 trigger shot Pregnyl - double dose. Clomid is a well-known and commonly prescribed fertility medication with a great reputation for increasing a woman’s fertility. Oct 09, 2008: Progesterone treatment while pregnant by: Wray Hi Vive The easiest way is to use your fingers. When your LH surges it will attempt to ovulate follicles with mature eggs but there is really to way to know which follicles have mature eggs and how many of those will release. acklyn, I will hope for ovulation on your right side! The first time I had iui, I only had two follicles (19 and 23) when they gave me the shot. What are the chances of conceiving twins while having two mature follicles? Posted on Sat, 7 Nov 2015. As the follicle matures, it increases in size and the number of granulosa cells also increases, as a result of which the estradiol levels rise progressively. I hope this helps. I took a trigger, had a IUI, and am currently pregnant with twins (fraternal most likely). May 7- Fertilization report= out of the 8 eggs, 6 were mature, and 4 fertilized. Acupuncturist said I should have done IUI that I already ovulated, and believes I should have not gone to retrieval. Ovidrel (choriogonadotropin alfa injection) is a fertility drug used to enhance and trigger ovulation. Get Now in your city! 3 mature follicles with clomid. Had 2 very large mature follicles. I dont know much about injectables besides the fact that they are expensive. We are trying a natural cycle this month and I went today for my cd12 scan. I was told the trigger shot works more quickly than that. 6, whereas for three and four follicles, this was 2. I had failed clomid attempts at 50, 100 and 150mg so the put me on femara, 5 mg and then she did a step up when I didn't quite respond(but still bigger follicles than I had with clomid)7. The trigger shot provides the final maturation signal to the developing follicle and sets ovulation in motion. Took PG test last night and this morning and BFP!!! Going for blood test tomorrow AM. At the time of the second egg retrieval , which is planned 36 hours after the second hCG shot , we expect to see intact follicles ; and expect to retrieve eggs from each of these follicles. Livingston on will follicles grow after trigger shot: Usually trial ultrasounds are done throughout the fertility process to monitor the follicular growth and development and to help minimize the risk of ovarian hyerpstimulation. Oh well, I’ll take what we can get!. The Trigger Shot. Hi, the gonadotropin injection and the trigger shot are two different things. cd 11- 125; cd 12 – trigger; cd13 – IUI # 2. Then we start testing for the LH Surge on CD 10, and if we don’t get the LH Surge by as early as CD 12 then we need to come in for an ultrasound so they can confirm the presence of a mature follicle. The doctor didnot suggest a trigger shot. There are actually three major estrogens, known as estradiol, estrone, and estriol. Usually, the hCG injection is given when four or more follicles have grown to be 18 to 20 mm in size and your estradiol levels are greater than 2,000 pg/ML. Before ovulation occurs, the average diameter of the dominant follicle is 22 to 24 mm (range 18-36 mm). I had a scan on CD11 and I had three follicles measuring 14. So they will keep monitoring and letting them grow. But even if both the follicles rupture, it is more likely that only one follicle will be fertilized. xxx Trigger shot went well last night - I did a cheapy HPT this morning just to see the two lines on there (never seen it before!). Gonal-F ® is a sterile, lyophilized powder intended for subcutaneous injection after reconstitution. There are several brand names for the hCG trigger shot including Ovidrel, Profasi, Pregnyl, and Novarel. Follicle Size before trigger shot Rey_S. And if I felt lousy, I could relax. This is a strange one, as my clinic would only do egg retrieval if you had more then 3 mature follicles. I only have one tube and I had 2 mature follicles with the trigger shot and IUI, my chances to get pregnant were 25% My change of having twins was less than 10%. He also said I had lots of little 11mms in there! Took my trigger shot (MAN I hate doing that)about 9pm tonight and my IUI is scheduled for Friday morning @ 9:30am. follicle size on 14th day is 17mm. Last but not least, different protocols may influence the size of follicles. so I know femara is an option. An oocyte is held in place with the large holding pipette on the left, while the smaller pipette is used to pick up a single live sperm. I had a mature follicle each cycle and didn't ovulate even with Ovidrel trigger shot. I knew that the 14mm would mature, but it was up in the air if the 10mm would mature in time (twins). When several mature follicles develop the couple and the fertility specialist can discuss multiple pregnancy. I just had my IUI yesterday. So 2 days later I've got my LH surge, my question is, if I trigger, do I base the timing of the IUI on the LH surge or the trigger shot?. She gave me two options - trigger in a couple days when we would expect it to be mature, or do a repeat ultrasound on CD14 to see how it has progressed so we can best time the trigger shot. If you are taking the hCG trigger shot, you will be monitored closely by your doctor. During fertility treatments, HCG may be given as a "trigger" so that a mature follicle will release its egg. We are trying natural way instead of IUI (intrauterine insemination) for now. The nurses and doc said that was great! But I had to take a trigger shot to induce ovulation since I don't on. Will add ganirelix back in when the lead follicle reaches 14mm to prevent premature ovulation. My doctor said if i have mature follicles he will have me take my Ovidrel (trigger) on friday night and it takes 36 hours from the trigger to ovulate. When an hCG injection is given, it causes the mature egg follicles that are in the ovary to finish maturing and be released. So they will keep monitoring and letting them grow. Any test taken within 10 days of the shot is going to give you a false positive. Multiples risks will depend on female age and the number and sizes of the follicles at the time of the HCG trigger shot; More about multiple birth risks with ovarian stimulation drug treatments; Reducing risks for multiple pregnancies. I am on clomid. Usually, your doctor will want to schedule your trigger shot—or hCG/LH injection—when your follicles are just about to reach full mature size. Follicle size 16. If the issue is there are too many follicles but just not maturing quite to the right size, again, the question you need to ask is whether you do the trigger shot to complete the cycle or let the body do it own work. She said there was. However, ovulation induction can increase the risk of multiples. 5 yrs -- unexplained infertility -. As of this morning I had at least 15 follicles greater than 11mm. Wondering About Follicle Size And Ovidrel Shot Question: Hi, I am on Gonal-f and my US (ultra-sound) yesterday showed I had 2 follicles measuring at 17mm and 14mm, my doctor told me to take one more shot of 75ui Gonal-f last night and to trigger with ovidrel tonight. How long after your trigger shot have you had your IUI? I went to RE this morning and I have 3 mature follicles. I hope some of the straggler follicles catch up before my egg retrieval at Saturday AM. about trying a trigger shot and while they've said they're open to me trying it if I really want, they seem to think continuing to use the OPK strips would be best. Most people experience a growth rate of about 6 inches per year, however, this can vary per individual, based on issues such as illness, nutrition and stress. After my trigger, I was told to bd at 24 and/or 36 hrs later. A trigger shot is needed to allow recovery of mature eggs that can be fertilized with IVF The problem in some patients is that although hCG is a very effective at triggering ovulation and maturation of eggs in the follicles, it lingers in the body and continues to support further hormone production in the ovaries. Comparison of efficacy of aromatase inhibitor and clomiphene citrate in induction of ovulation in polycystic ovarian syndrome. Today’s u/s showed 8 follicles but the tech told me that it looked like I only had about 2-3 “mature” follicles. Which I make on my own every month. I did ultrasound yesterday cd15 and I had two follicles about 16 to 18mm, the doctor wanted me to do the shot today since yesterday the follicles too small and if wait he is afraid too late. I still have to hear it from the nursing team. Ovarian stimulation protocols are developed to achieve a balance of high oocyte yield and resulting quality. Usually, your doctor will want to schedule your trigger shot—or hCG/LH injection—when your follicles are just about to reach full mature size. I just had an u/s and discovered I have two mature follicles. At what follicle size were you triggered? - posted in IVF Ages 35+: Hi all, I was probably triggered too early last time and this second IVF cycle, we are waiting a little longer. When i was scanned I had 4 really good follicles and then plus my trigger shot. ) My left ovary had 4-5 follicles but they weren’t as large. 52), but they also grew more slowly than they did during IUI #1, even though we doubled the dose of Bravelle! Weird. I was told the trigger shot works more quickly than that. This happened to me on my 2nd Cycle of IUI. My first cycle I didnt even know anything. I am thinking from seeing other posts her quoting follicles over 20mmcould this be my problem they are doing it too soon so the eggs are not mature. 5,16,15,5 follicles. I also had one at 11mm, which might grow large enough by ovulation to possibly contain a mature egg. Giving hCG would not be enough to achieve maturity. It is now Cycle Day 23; 10 days since the trigger shot, and supposedly 8 days post ovulation. Have been TTC for 1. This can result in the eggs being lost in the follicular fluid that is released from the ovary at the time of ovulation. Most controlled ovarian stimulation cycles start with the injection of follicle stimulation hormone-FSH-at this time. I had two mature follicles. Human Chorionic Gonadotropin (HCG): 5000 to 10,000 units IM once 1 day following the last dose of menotropins. When I was taking 50mg of Clomid they though I would end up developing 2 mature follicles. Clomid/timed intercourse (disastrous) round 2: started 50mg of Clomid on CD2 for 5 days. In my case, I use 50% maturity as my baseline measure, since follicles tend to grow at different rates. One question that occurs obsessively on infertility groups and forums is "what size should my follicles be at trigger?". The goal is to have the majority of follicles between 18mm to 22mm since these are the follicles most likely to contain mature eggs. Hello, I am 42 yrs old, have 2 gown teens from my late husband. 5 yrs -- unexplained infertility -. I am concerned that my follicles were not mature enough, epsecially since my estrogen was a bit low. The optimal size of the leading follicle in ovulation induction with CC and Letrozole is similar for both drugs, 24mm for CC and 24. With only doing hte. I also had one at 11mm, which might grow large enough by ovulation to possibly contain a mature egg. Hi, Clomid does not always work to produce the mature follicles. I hope this helps. Good luck xxx #6 Vici , Oct 30, 2010. Chances are that you will only release 2 mature eggs, the trigger shot gives them a little extra boost too so by the time they release they should be between 20mm and 24mm and those are good sizes. If you become pregnant during a treatment cycle, OHSS may worsen as your body begins producing its own HCG in response to the pregnancy. If the timing of the injection is successful, the mature eggs should be available for fertilization through intrauterine insemination (IUI) or timed intercourse, or for harvesting for in vitro fertilization (IVF). I used 50 mg of Clomid, then Day 7 and Day 9 (150 mg each of Follistem). I was giving the trigger shot and told to have sex that night. The trigger is a shot in the butt to “ripen” the egg so that the eggs would ovulate 48 hours later. The pooled OR for pregnancy after two follicles as compared with monofollicular growth was 1. Then my RE performs the IUI 36 hours later. But that one stuck and is due in Feb. There is 1 egg in each follicle. Eggs from follicles measuring about 20mm at trigger have the highest *chance* of being mature, but that doesn't mean that they will be, or that eggs from other follicles won't. When the leading follicle reached 18 mm in diameter, final oocyte maturation was triggered by either urinary HCG (5000 IU or 10,000 IU; Lizhu Pharmaceutical Trading Co. Yesterday was day 4 of stims and my ultrasound/blood work. When I saw my doctor the morning of my trigger shot I had 2 follicles mature and 1 that he said "might" catch up before the trigger shot that night. My doctor was surprised to see already a 22. This month, I have two mature follicles, one on each side. When an hCG injection is given, it causes the mature egg follicles that are in the ovary to finish maturing and be released. With 6 mature follicles and 2 catching up mine was at 1830, so we had a possibility of at least 6 of them being fully mature. The optimal size of the leading follicle in ovulation induction with CC and Letrozole is similar for both drugs, 24mm for CC and 24. HCG is usually given 34 to 36 hours before egg retrieval, since release usually occurs naturally 36-plus hours after administration, the University of Maryland Medical Center explains. Are 16mm follicles typically mature enough to produce an egg?. If you’re like me and have a lot of tiny follicles all over your ovaries, you need to talk to a doctor about fertility medication to help mature the follicles so you can get pregnant. Most look for the 18mm follicles and go for it. BUT THE NERSE GAVE ME HCG TRIGGER SHOOT WITHOUT CONFIRMATION FROM MY DOCTOR !!! Now I am really worried that my follicles are a little bit two small! Could you let me what is your follicle size when you had your trigger shot!. The Clomid for me has been doing its job, which is good to hear!! According to my RE the "goal" is to get as many follicles between a 16 & 20 without them getting too big before the trigger shot.
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